Sides of town for hotels?

I got 1:46 for my housing lottery time, so probably not good enough for downtown, but maybe good enough for N/S/E/W side. It's my first gen con, and I'm not very familiar with Indianapolis.

Is there a side of town I should shoot for? One I should avoid? One with worse traffic to the con? Better food nearby? Bus lines? Or should I just go for the closest possible place?