Unplugging everything

Hi, I've just bought a new PC and I didn't pay much attention to the cable management, and I want to do so in future. And that's why I'm asking. If I unplug everything from mobo etc. do I have to do something after plugging it again?(For example bios update or something like that)

Hi, I've just bought a new PC and I didn't pay much attention to the cable management, and I want to do so in future. And that's why I'm asking. If I unplug everything from mobo etc. do I have to do something after plugging it again?(For example bios update or something like that)